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After withdrawal from systemic corticosteroids, a number of months are required for recovery of hypothalamic- pituitary -adrenal HPA function. Patients who have been previously maintained on 20 mg or more of prednisone or its equivalent may be generic Fluticasone and Salmeterol Pills Purchase susceptible, particularly when their systemic corticosteroids have been almost completely withdrawn. During this generic Fluticasone and Salmeterol Pills Purchase of HPA suppression, patients may exhibit signs and symptoms of adrenal insufficiency when exposed to trauma, surgery, or infection particularly gastroenteritis or generic Fluticasone and Salmeterol Pills Purchase conditions associated with severe electrolyte loss.

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In addition, because there is a natural increase in corticosteroid production during pregnancy, most women will require a lower exogenous corticosteroid dose and many will not need corticosteroid treatment during pregnancy. These included precocious eyelid openings, cleft palate, sternebral fusion, limb and paw flexures, and delayed ossification of the frontal cranial bones. Nonteratogenic Effects Hypoadrenalism may occur in infants born of mothers receiving corticosteroids during pregnancy. Such infants should be carefully monitored.

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An imbalance in the proportion of children entering puberty between groups and a higher dropout rate in the placebo group due to poorly controlled asthma may be confounding factors in interpreting these data. A generic Fluticasone and Salmeterol Pills Purchase subset analysis of children who remained prepubertal during the trial revealed growth rates at 52 weeks of 6. In children aged 8. The clinical relevance of these growth data is not certain. The potential growth effects of prolonged treatment should be weighed against the clinical benefits obtained. In addition, as with other products containing beta2-agonists, special caution should be observed when using ADVAIR HFA in geriatric patients who have concomitant cardiovascular disease that could be adversely affected by beta2-agonists.

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